Research Associate III in our Pharmacodynamics Assay Development and Implementation Section to manage an assay development project under direction of the lead scientist and perform immunoassay prototyping, development and validation, for application in clinical patient drug response monitoring that supports novel clinical trials in oncology. You will be the prime mover in assay method transfer across laboratories, including training of staff scientists. Will quantitatively analyze assay results and continuing assay performance. Other responsibilities include data triage, quality control reagent preparation and evaluation, laboratory training and performance monitoring.
Bachelor’s degree from an accredited college/university in a field related to biomedical research required or four (4) years equivalent experience in the appropriate field in lieu of degree. Foreign educated candidates who have completed part or all of their education outside of the United States must have their foreign education evaluated by an SAIC-approved accrediting organization to assure that it has met the equivalency of the qualifications of degree work in the United States. In addition to educational requirements, a minimum of eight (8) years related biomedical experience following completion of educational requirements, including at least two years of laboratory assay design experience in Immunohistochemistry, in a clinical laboratory, lab medicine or hematology/pathology lab service, early clinical trial laboratory, or similar clinical lab environment. Similar experience in ELISA may be substituted but the primary job responsibility will be in IHC/IFA, therefore experience with epifluorescence microscopy is necessary. Demonstrated competence, knowledge, critical thinking skills and experience in: immunoassay development; test validation; clinical specimen processing; data analysis, reporting and confidentiality; GLP principles and practice, including QC and change control; laboratory assay technical transfer and proficiency testing; clinical testing and the use of testing instrumentation; organizing and operating a clinical laboratory; and the integration of PC-based tools into laboratory operations. Must be proficient in two or more testing technologies including ELISA, IHC, IFA, digital imaging and related software, and comfort with computerized quantitation. Shows evidence of successful independent judgment relating to specialized activities concerning clinical assay validation and specimen testing. Must be able to work flex hours and be able to adapt schedule to meet clinical data reporting requirements. Experience in design and development of Western blotting, IEF, quantitative immunoassay methods. Experience in isolation of proteins and nucleic acids from human solid tissues and blood; experience in blood cell separation/purification This position is subject to obtaining a Public Trust Clearance.
SAIC Frederick, Inc., the operations and technical support contractor to the National Cancer Institute-Frederick, offers an excellent compensation package for our position. For additional information and immediate consideration, please apply online for position #143430 at our website: http://saic-frederick.com
SAIC is an equal opportunity employer and values cultural diversity in the workplace.
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